In a pure or vast-majority virtual environment? You might be looking for Backup and Recovery for Virtual Environments.

Backups in non-virtualized or mixed environment enterprises might not be able to take advantage of all the feature sets available to backup products that leverage hypervisor-level tools. However, there are good tools available which work with both physical and virtual environments for something which can grow as a company moves in the direction of virtualization.

Unitrends

• http://www.unitrends.com/
• Available as an appliance or a virtual appliance
  • Appliance Family
    http://www.unitrends.com/products/appliance-family.html
    
  • Unitrends Enterprise Backup virtual appliance
    http://www.unitrends.com/unitrends-enterprise-backup.html
• vSphere, Hyper-V, and physical hosts
• 15 minute RPO with the Appliance and as little as 60 seconds with UEB
• Appliance can be used as a DR host, booting backup images
• UEB gives the first four workloads to be backed up for free

AppAssure Replay (bought by Dell Feb 2012)

• http://www.appassure.com/server-backup-and-replication/
• Provides a single product for both physical and virtual workloads.
• vSphere, Hyper-V, XenServer, and physical hosts
• Automatic backup verification.
• Both Bare Metal, application object, and file level restore.
• 5 minute Recovery Point Objective